A study appearing in the International Journal of Epidemiology (1998, Aug, 27(4):667-71) found that people with 15 or more amalgam fillings had a 250% greater risk of developing multiple sclerosis than controls. Mercury has been found to accumulate preferentially in the primary motor function related areas such as the brain stem, cerebellum, rhombencephalon, dorsal root ganglia, and anterior horn motor neurons, which enervate the skeletal muscles. MS patients have been found to have much higher levels of mercury in their cerebrospinal fluid, compared to controls according to a study appearing in Environmental Research (1994; 65: 195-206). German studies have found that MS patients usually have higher levels of mercury than normal controls (B.A.Weber, “The Marburg Amalgam Study”, Arzt und Umwelt, Apr, 1995; (266 cases). Mercury toxicity may be worth considering in MS patients.