Recent research, appearing in Journal of Nutritional Health and Aging.  (2004; 8(4):226-32 (ISSN: 1279-7707) looked at vitamin intake and its relation to cognitive function and psychological well-being in over 1000 middle-aged Australian men and women. Specifically dietary intake of folic acid, vitamin B6 and vitamin B12 were beneficial. The subjects filled out questionnaires to determine dietary intake of these nutrients. The researchers concluded: “Vitamin B-12 and B-6 intakes may be positively related to the memory performance of middle-aged men and intakes at around the RDI are associated with better memory functioning for women. The investigation of the dose-response effects of B vitamin supplementation on cognition and mood in middle-aged men and women using objective measures of cognition and accounting for the influence of confounding factors such age and education would be informative.”