ALT stands for alanine aminotransferase; it is a substance that is released into the blood when liver cells are damaged. ALT levels in the serum will give you an idea if there is any liver cell damage occurring. A randomized, single-blind, placebo-controlled, 5-treatment, parallel-group, inpatient, diet-controlled (meals provided), longitudinal study of 145 healthy adults, appearing in the Journal of the American Medical Association (Vol. 296 No. 1, July 5, 2006) indicates that acetaminophen use, even a recommended doses, causes liver damage. The subjects were given either four grams of acetaminophen (the maximum recommended daily dose) or a placebo for 14 days. The use of the acetaminophen increased ALT levels to nearly five times normal in 19% of the participants. No such increases were noted in the placebo group
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