A double-blind, placebo-controlled study published in the American Journal of Psychiatry (2006;163(6):1098–1100) evaluated the effects of omega-3 fatty acid supplementation on depression in children. Twenty children participated and were randomly assigned to receive either:

  • A combination of EPA and DHA (omega-3 fatty acids), or

  • A placebo

Researchers assessed depressive symptoms at the start of the study and again at 2, 4, 12, and 16 weeks using multiple validated tools, including:

  • Children’s Depression Scale

  • Children’s Depression Inventory

  • Clinical Global Impression

Study Results

By the end of the 16-week trial:

  • 7 out of 10 children receiving omega-3s experienced at least a 50% improvement in their depression scores.

  • No improvement was observed in the placebo group.

These findings suggest that EPA and DHA may play a supportive role in emotional health in some children. More research is needed to confirm these effects in larger populations.

Educational only — not medical advice.