Sjögren’s (pronounced SHOW-grins) syndrome is an autoimmune condition best known for causing dry eyes and dry mouth. It often occurs alongside other autoimmune disorders, such as rheumatoid arthritis or lupus. In Sjögren’s syndrome, the immune system targets moisture-producing glands, especially those that make tears and saliva, which can lead to persistent dryness and discomfort.
Although Sjögren’s syndrome can develop at any age, it is most commonly diagnosed in people over 40 and is far more common in women.
Researchers have explored whether nutrient status may be linked with certain complications seen in Sjögren’s syndrome. A study published in the Journal of Autoimmunity (Volume 39, Issue 3, September 2012, Pages 234–239) compared vitamin D levels in 176 patients with Sjögren’s syndrome and 163 healthy controls. The researchers found that lower vitamin D levels were associated with a higher prevalence of peripheral neuropathy and lymphoma in patients with Sjögren’s syndrome. Vitamin D may be useful for autoimmune diseases in general.
These findings do not establish cause and effect, but they suggest that vitamin D status may be relevant when considering overall health risks and immune regulation in people with Sjögren’s syndrome. Further research is needed to clarify the role vitamin D may play in disease severity or complications.
