According to a study published in the Journal of Nutrition (2010; 140(2):338–347), there may be a relationship between folate status and depression. This population-based, cross-sectional study included 1,681 adults between the ages of 30 and 64. The researchers found that men with the highest serum folate levels had nearly a 40% lower score on the Center for Epidemiologic Studies Depression Scale compared with men with lower folate levels. Folate is found naturally in fresh produce, and the terms folate and folic acid come from the word “foliage.” The study suggested that improving dietary intake of folate-rich foods was associated with lower depression scores in men, but not in women.