Iodine is essential, but unlike many vitamins, it can significantly affect thyroid physiology.

Some Clinicians Use High Doses of Iodine

Dr. David Brownstein and other holistic doctors give very high doses of iodine (90 times the RDA, and even more). The argument is that deficiency is widespread and severe. Dr. Brownstein’s book is full of clinical examples and stunning results. Many clinicians swear by iodine, especially when dealing with fibrocystic breasts or PCOS—this is controversial. Some even recommend it for Graves’ disease—which traditional medicine cautions against. Most people who take higher doses of iodine probably do very well. The challenge is identifying the small percentage of people who won’t.

Some Doctors Are Concerned About High Doses of Iodine

Not everyone tolerates iodine well. The Wolff–Chaikoff effect is an autoregulatory thyroid mechanism where a sudden surge of excess iodine temporarily inhibits the gland from synthesizing and releasing thyroid hormones. This is hypothyroidism triggered by a high dose of iodine. The good news is that things usually return to normal once the iodine is discontinued. Some patients may experience other problems:

  • autoimmune thyroid disease
  • nodules
  • iodine-induced hyperthyroidism

Unlike the Wolff–Chaikoff effect, iodine-induced hyperthyroidism may not resolve simply by discontinuing iodine. Because thyroid nodules can increase this risk, it is important to know whether they are present before considering aggressive iodine therapy.

Sometimes There Is a Problem with Too Much Iodine

Unfortunately, there is no simple blood test that tells us exactly who needs more iodine or who will react poorly to higher doses. That uncertainty is one reason experienced clinicians often monitor thyroid function carefully when using larger doses.

Common Sense and Iodine

I believe iodine deserves respect. It is an essential nutrient that can produce remarkable results in some people, but it is not a supplement to experiment with casually. If you’re considering higher doses, work with a healthcare professional familiar with thyroid physiology, especially if you have a history of thyroid disease or thyroid nodules.

Because thyroid nodules can increase this risk, it is reasonable to consider whether they are present before beginning aggressive iodine therapy. Thyroid nodules are often detected with a simple thyroid ultrasound.

Most supplements don’t dramatically change the function of any organ. Iodine is the exception.