Lower Levels of CoQ10 Found in Women on Hormone Replacement Therapy

Posted by Whole Health Web Admin | Oct 14, 2016 | Research Articles, Women's Health | 0 |

Research published in Biofactors (2005; 25(1–4):61–66) examined the relationship between hormone replacement therapy (HRT) and antioxidant status, including coenzyme Q10 (CoQ10), in women. The study included 50 premenopausal women, 33 healthy postmenopausal women not using HRT, and 15 postmenopausal women receiving HRT.

Overall, postmenopausal women not using HRT had higher serum CoQ10 levels than premenopausal women. In contrast, postmenopausal women using HRT had lower levels of CoQ10 and gamma-tocopherol, despite having higher alpha-tocopherol levels.

These findings suggest that hormone replacement therapy may alter antioxidant balance, including a reduction in CoQ10 levels, which could have implications for mitochondrial function and oxidative stress in postmenopausal women.

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