Small controlled studies suggest chromium—particularly in yeast-bound form—may modestly improve fasting glucose and oxidative stress markers in type 2 diabetes, though findings are inconsistent and effects appear limited. In one double-blind, placebo-controlled study appearing in Biological Trace Element Research (2006; 109(3): 215-30), the effect of chromium enriched yeast was tested on 36 subjects with type 2 diabetes.  The subjects were randomly divided into two groups; one group received 400 mcg of chromium (in yeast) and the other group received a placebo. The supplemented group enjoyed a lowering in fasting blood glucose and in oxidative stress markers.