Summary 

A 2012 long-term animal study raised concerns about genetically modified corn and glyphosate-based herbicides (Roundup). Researchers reported hormonal changes, liver and kidney problems, and tumor development in rats fed GMO maize or exposed to Roundup in drinking water. Although the study was initially published in Food and Chemical Toxicology, it was later retracted and republished after debate over methodology and data interpretation.

More recent research continues to examine glyphosate’s effects on the liver, kidneys, and endocrine system. Several animal and cell studies report oxidative stress and mitochondrial damage linked to glyphosate exposure, while human studies have found higher urinary glyphosate levels in chronically ill individuals compared to healthy controls.

However, regulatory agencies, including the European Food Safety Authority (EFSA) and the U.S. EPA, maintain that glyphosate is unlikely to pose a cancer risk at typical dietary exposure levels. The topic remains under review as more long-term studies emerge.

(Educational only; not medical advice.)