A preliminary study at the University at Buffalo evaluated the effects of an eight-week individualized resistance-exercise program for children with juvenile arthritis. The results showed substantial improvements in strength, endurance, pain levels, and overall physical functioning.

According to Nadine Fisher, Ed.D., assistant professor of occupational therapy and rehabilitation medicine, the improvements were greater than expected. “We anticipated some changes,” she noted, “but the degree of improvement was remarkable.” Some participants improved by as much as 200%.

Because juvenile arthritis is an autoimmune condition, the study also looked at immune markers. Children who exercised had lower levels of pro-inflammatory cytokines and higher levels of anti-inflammatory compounds compared to those who did not participate in the program.

Strength and endurance gains were notable:

  • Quadriceps strength increased by 48%; endurance by 32%

  • Hamstring strength increased by 99%; endurance by 59%

  • Speed of muscle contraction increased by 51%

  • Physical capability improved by 32%

  • Pain decreased by nearly 50%

  • Disability scores and medication use decreased by 25%

These preliminary findings suggest that supervised resistance exercise may play a supportive role in improving physical function and reducing pain in children with juvenile arthritis.