Research published in Experimental Physiology (December 2008; Volume 93, Issue 12, Pages 1263–1272) examined the effects of vitamin E supplementation on inflammation in an animal model. In this study, mice were assigned to receive either vitamin E or a placebo for three days.
After the supplementation period, the mice were injected with Escherichia coli lipopolysaccharide (LPS), a bacterial toxin commonly used to induce an inflammatory response. Levels of inflammatory signaling molecules (cytokines) were significantly lower in the vitamin E–supplemented mice compared with those in the control group.
These findings suggest that vitamin E supplementation influenced inflammatory responses in this experimental model.