A double-blind, placebo-controlled study published in Diabetic Medicine examined the effects of omega-3 fatty acid supplementation in patients with type 2 diabetes. In the 12-week study, 97 subjects received either four grams of fish oil per day or a placebo.

Patients receiving fish oil experienced a reduction in serum creatinine levels, a marker commonly used to assess kidney function. This finding suggests a potential protective effect on renal function, which is clinically relevant given the increased risk of kidney disease in people with diabetes. The supplemented group also showed a reduction in triglyceride levels, a well-established benefit of omega-3 fatty acids.

While the study was relatively short and not designed to assess long-term kidney outcomes, the results are consistent with the known anti-inflammatory and lipid-lowering effects of omega-3 fatty acids.