Editor’s Note: This article was originally published in 2018 and is preserved for historical interest. Some recommendations, regulations, and scientific evidence have changed since it was written. It reflects the research and perspectives available at that time.
According to a small research study (Biochem Biophys Res Commun 100:972-7, 1981). A small group of students (12/27) who were not supplemented were challenged with a large dose MSG and showed characteristic symptoms. For 12 weeks nine of the students received 50 mg. of pyridoxine (vitamin B6) per day, the other three took a placebo. When challenged with MSG after the supplementation, 8/9 of the supplemented students did not react to the MSG. Another study, conducted on rats appeared in J Nutr. (1972 Jul;102(7):835-40) showed B6 to help with the utilization of MSG.
