According to research published in the Journal of the American Medical Association (January 23, 2008; 299:308–315), low vitamin E levels may be linked with physical decline in older adults. The study followed 698 adults living in Tuscany, with an average age of 73.7 years. Participants completed baseline testing and were re-evaluated three years later.

Physical performance was assessed using the Short Physical Performance Battery (SPPB), which includes walking speed, chair stands, and balance tests. Two factors were consistently associated with physical decline:

  • Low serum vitamin E (alpha-tocopherol) in adults aged 70–80

  • Being over age 81

One explanation suggested by the authors is oxidative stress. Vitamin E is a key fat-soluble antioxidant, and lower levels may leave tissues more vulnerable to oxidative damage, potentially accelerating age-related degenerative processes.