Volatile organic compounds (VOCs) are chemicals released into the air from many common household products, including paints, cleaning products, air fresheners, solvents, and new carpets. These chemicals can irritate the airways and contribute to inflammation.

Early research suggested that children exposed to higher levels of VOCs were more likely to experience asthma symptoms. Since then, larger and more recent studies have supported this association, showing that indoor VOC exposure is linked with both increased asthma symptoms and higher asthma risk, especially in children [1].

VOCs are known to promote airway irritation, oxidative stress, and immune activation, all of which can worsen asthma or make airways more sensitive over time. Children are particularly vulnerable because their lungs and immune systems are still developing.

Indoor VOC levels tend to be higher in homes with poor ventilation, recent renovations, new furnishings, or indoor smoking. Reducing exposure by improving ventilation, avoiding unnecessary chemical products, and allowing new materials to off-gas may help support respiratory health.

More recent research supports these early findings [2,3]. It may be possible to measure exhaled VOCs in asthma patients [4].

Indoor exposure to VOCs can be from paints, cleaners, smoke, new carpets, and air fresheners. Increasing ventilation, avoiding heavily fragranced products, and choosing low-VOC paints/furniture are among the strategies that can help to manage risks.

Click for strategies to help asthma symptoms.

References:

  1. Thorax. 2004 Sep;59(9):746–751. Association of domestic exposure to volatile organic compounds with asthma in young children
  2. Environmental Research Volume 202, November 2021, 111631 Indoor PM2.5, VOCs and asthma outcomes: A systematic review in adults and their home environments
  3. Environmental Pollution Volume 321, 15 March 2023, 121103 Volatile organic compounds (VOC) in homes associated with asthma and lung function among adults in Northern Europe
  4. Allergol Int. 2024 Oct;73(4):524-531 Identification of exhaled volatile organic compounds that characterize asthma phenotypes: A J-VOCSA study